Golden Globes 2012 Fashion: Red Carpet Roundup

Reese Witherspoon, Charlize Theron and Nicole Richie shine.
By Christina Garibaldi, with reporting by Josh Horowitz


Reese Witherspoon attends the 2012 Golden Globes
Photo: Getty Images

On Sunday night, the hottest celebrities in Hollywood gathered for the 2012 Golden Globes to celebrate one of the biggest nights in movies, television, and, of course, fashion. The stars shone bright on the red carpet, showing off gorgeous mermaid-style gowns, plunging necklines and sparkling headbands.

Yet, it wasn't all about bright colors: The big trend for the night was nude-hued gowns, worn by everyone from Jessica Biel and Heidi Klum to "Modern Family" actress Sarah Hyland. "This one is really different," Hyland told MTV News of her beige lace Dolce & Gabbana gown. "I never really wore lace before so I feel very feminine in it. It's very vintage-y, classy, and I like that."

While Hyland's dress was covered in lace, first-time attendee and Best Supporting Actress nominee for "The Help," Jessica Chastain decided to adorn herself from head to toe in pearls. "It was love at first sight with this dress," Chastain said of her white Givenchy gown. "This is my first Golden Globes. There's something very pure about this dress. I'm a very pure girl."

Looking radiant in a silver Julien Macdonald gown was Nicole Richie, who finished off her look with her very own House of Harlow bag. "I thought she looked amazing," Celebuzz producer Rachel Maresca told MTV News. "We haven't seen her on a red carpet in a long time, and she came out wowing everybody. She's in Julien Macdonald with a fully beaded dress. She said it was little bit heavy, but she looked very comfortable in it, and she's rocking a House of Harlow, her own designed bag."

A-list actresses flooded the red carpet, including Angelina Jolie in a draped ivory Atelier Versace gown with red accents, Charlize Theron in a pink Dior Couture gown complete with high slit and Cartier headband, and Emma Stone in a purple and red accent Lanvin gown with a plunging neckline.

Yet, it was a lady in red that might have stolen the show: Reese Witherspoon dazzled in a tight-fitted scarlet Zac Posen dress with a sweetheart neckline, deciding to keep the rest of her look laidback with wavy hair.

"Her hair for me looked 'gorgeous without trying' type of look," Maresca said. "The dress was made for her; it looks great."

Who do you think was the best dressed at the Golden Globes? Sound off below!

Check out the 2012 Golden Globes winners, our fashion coverage from the Golden Globes red carpet, and stay with MTV Style during awards-show season, and every day!

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Source: http://www.mtv.com/news/articles/1677371/golden-globes-best-worst-fashion.jhtml

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'Napoleon Dynamite' Series Premiere: Napoleon vs. Kip In 'Thundercone' (VIDEO)

The "Napoleon Dynamite" (Sun., 8:30PM on Fox) Series Premiere welcomed fans back to the wacky world of the Dynamite family. And this time, the Dynamites are animated.

In an effort to banish his unsightly acne, high school student Napoleon (Jon Heder) turns to a banned skin cream.

However, the side effects mean that he becomes super strong and full of rage, and the fomerly mild-mannered 16 year-old goes ahead and steals the lovely Misty (Amy Poehler) away from older brother -- and cage-fighting enthusiast -- Kip (Aaron Ruell).

Unfortunately for Napoleon, Kip figures out his secret and turns the tables on him. So the Dynamite siblings end up fighting each other for the hand of Misty. In a cage, natch.

A surprisingly ripped Kip, face a-blazing, goes all "Thunderdome" on his little brother and shows off some fancy moves, leaving Napoleon to question, "When the heck did you learn to walk on stilts?"

And, seeing Kip all pumped-up leads Misty to change her mind and decide that Kip, not Napoleon, is the one for her.

Follow the new adventures of "Napoleon Dynamite" on Sunday nights, 8.30 p.m. EST on Fox.

TV Replay scours the vast television landscape to find the most interesting, amusing, and, on a good day, amazing moments, and delivers them right to your browser.

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Source: http://www.huffingtonpost.com/2012/01/16/napoleon-dynamite-series-premiere-video_n_1208330.html

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Great White Shark Caught On Tape by Two Hilarious Pidgin Fishermen (Little green footballs)

It?s 10pm And You Need A HDMI Cable ? No Problem This Week in Vegas

hdmiTechCrunch TV is using a LiveU mobile pack provided by our partner Ustream for our live streaming coverage from CES. Our camera connects to the pack via a HDMI connector cable. But at the end of our evening Showstoppers coverage, the HDMI plug snapped and broke. At 10pm in Las Vegas, how do you find a replacement HDMI plug? Actually, of all the places in the world to have this happen, we were in the right place.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/qj3E3cyCjtg/

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Things Entrepreneurs Should Avoid When Raising Capital

_1101957_money300Alright, in my last post I argued that bootstrapping is just as over-rated as raising venture capital. But for those who decide to pursue fundraising, here are some things entrepreneurs should avoid when raising capital. For all of the talk about how much excess capital there is, it?s actually hard to raise capital because very few projects fit the VC profile?even though many VC-funded projects come across as frivolous, me-too projects.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/SQ2LQW1K0W8/

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Diablo: IncGamers ? Investing in Videogame Stocks ? Activision ...

Posted 12 January 2012 by Elly

You may well be planning to play the Diablo 3 Market when the game is released but what about really investing in Blizzard or even other videogame publishers. An article called Investing in Video Game Stocks: A How-To Guide has appeared on Fool.com which analysis some of the recent trends and what stocks are worth investing in.

In their article Activision Blizzard is placed as a Strong buy according to??Zacks Investment Research so perhaps this is something to pay attention to. As far as I know Flux has some cash invested in Blizzard so I?m pretty sure he watches the values carefully so he can make his millions ;)

Source: http://diablo.incgamers.com/blog/comments/investing-in-videogame-stocks-activision-blizzard

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Getting cancer cells to swallow poison

[ Back to EurekAlert! ] Public release date: 9-Jan-2012
[ | E-mail | Share Share ]

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital

Nanotechnology researchers develop new strategy to deliver chemotherapy to prostate cancer cells

BOSTON, MA -- Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Omid Farokhzad, MD, Brigham and Women's Hospital (BWH) Department of Anesthesiology Perioperative and Pain Medicine and Research.

In their latest study with researchers from Massachusetts Institute of Technology (MIT) and Massachusetts General Hospital, the BWH team created a drug delivery system that is able to effectively deliver a tremendous amount of chemotherapeutic drugs to prostate cancer cells.

The study is electronically published in the January 3, 2012 issue of ACS Nano.

The process involved is akin to building and equipping a car with the finest features, adding a passenger (in this case the cancer drug), and sending it off to its destination (in this case the cancer cell).

To design the "vehicle," researchers used a selection strategy developed by Farokhzad's team that allowed them to essentially select for ligands (molecules that bind to the cell surface) that could specifically target prostate cancer cells. The researchers then attached nanoparticles containing chemotherapy, in this case docetaxel, to these hand-picked ligands.

To understand Farokhzad's selection strategy, one must understand ligand behavior. While most ligands mainly have the ability to bind to cells, the strategy of Farokhzad and his colleagues allowed them to select specific ligands that were not only able to bind to prostate cancer cells, but also possessed two other important features: 1) they were smart enough to distinguish between cancer and non-cancer cells and 2) they were designed to be swallowed by cancer cells.

"Most ligands are engulfed by cells, but not efficiently," said Farokhzad. "We designed one that is intended to be engulfed."

Moreover, the ability for a ligand to intentionally be engulfed by a cell is crucial in drug delivery since it enables a significant amount of drug to enter the cancer cell, as opposed to remaining outside on the cell surface. This is a more effective method for cancer therapy.

Another important aspect of this drug delivery design is that these ligand-nanoparticle components are able to interact with multiple cancer markers (antigens) on the cell surface. Unlike other drug delivery systems, this makes it versatile and potentially more broadly applicable.

According to the study's lead author, Zeyu Xiao, PhD, a researcher in the BWH Laboratory of Nanomedicine and Biomaterials, current strategies for targeting nanoparticles for cancer therapy rely on combining nanoparticles with ligands that can target well-known cancer markers. Such strategies can be difficult to execute since most cancer cells do not have identifiable cell surface markers to distinguish themselves from normal cells.

"In this study, we developed a unique strategy that enables the nanoparticles to specifically target and efficiently be engulfed into any desired types and sub-types of cancer cells, even if their cancer markers are unknown," said Xiao. "Our strategy simplifies the development process of targeted nanoparticles and broadens their applications in cancer therapy."

###

This research was supported by the National Institutes of Health, the David Koch-Prostate Cancer Foundation, and the USA Department of Defense Prostate Cancer Research Program.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 9-Jan-2012
[ | E-mail | Share Share ]

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital

Nanotechnology researchers develop new strategy to deliver chemotherapy to prostate cancer cells

BOSTON, MA -- Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Omid Farokhzad, MD, Brigham and Women's Hospital (BWH) Department of Anesthesiology Perioperative and Pain Medicine and Research.

In their latest study with researchers from Massachusetts Institute of Technology (MIT) and Massachusetts General Hospital, the BWH team created a drug delivery system that is able to effectively deliver a tremendous amount of chemotherapeutic drugs to prostate cancer cells.

The study is electronically published in the January 3, 2012 issue of ACS Nano.

The process involved is akin to building and equipping a car with the finest features, adding a passenger (in this case the cancer drug), and sending it off to its destination (in this case the cancer cell).

To design the "vehicle," researchers used a selection strategy developed by Farokhzad's team that allowed them to essentially select for ligands (molecules that bind to the cell surface) that could specifically target prostate cancer cells. The researchers then attached nanoparticles containing chemotherapy, in this case docetaxel, to these hand-picked ligands.

To understand Farokhzad's selection strategy, one must understand ligand behavior. While most ligands mainly have the ability to bind to cells, the strategy of Farokhzad and his colleagues allowed them to select specific ligands that were not only able to bind to prostate cancer cells, but also possessed two other important features: 1) they were smart enough to distinguish between cancer and non-cancer cells and 2) they were designed to be swallowed by cancer cells.

"Most ligands are engulfed by cells, but not efficiently," said Farokhzad. "We designed one that is intended to be engulfed."

Moreover, the ability for a ligand to intentionally be engulfed by a cell is crucial in drug delivery since it enables a significant amount of drug to enter the cancer cell, as opposed to remaining outside on the cell surface. This is a more effective method for cancer therapy.

Another important aspect of this drug delivery design is that these ligand-nanoparticle components are able to interact with multiple cancer markers (antigens) on the cell surface. Unlike other drug delivery systems, this makes it versatile and potentially more broadly applicable.

According to the study's lead author, Zeyu Xiao, PhD, a researcher in the BWH Laboratory of Nanomedicine and Biomaterials, current strategies for targeting nanoparticles for cancer therapy rely on combining nanoparticles with ligands that can target well-known cancer markers. Such strategies can be difficult to execute since most cancer cells do not have identifiable cell surface markers to distinguish themselves from normal cells.

"In this study, we developed a unique strategy that enables the nanoparticles to specifically target and efficiently be engulfed into any desired types and sub-types of cancer cells, even if their cancer markers are unknown," said Xiao. "Our strategy simplifies the development process of targeted nanoparticles and broadens their applications in cancer therapy."

###

This research was supported by the National Institutes of Health, the David Koch-Prostate Cancer Foundation, and the USA Department of Defense Prostate Cancer Research Program.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/bawh-gcc010912.php

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HBT: Dodgers and Fox settle TV rights dispute

The last possible thing preventing Frank McCourt from meeting his deadline to sell the Dodgers by April 30 was the ongoing litigation he and the Dodgers had with Fox over the Dodgers? desire to auction off future broadcast rights prior to a sale. ?That potential barrier is gone now, as the Dodgers and Fox have settled the lawsuit, with the Dodgers agreeing not to sell TV rights until after November 30 as Fox had desired. ?Bill Shaikin:

The impetus for the settlement was the ruling last month that stayed the Dodgers from selling their television rights along with the team. U.S. District Judge Leonard Stark indicated he would probably make that ruling permanent.

So, yeah, when that thing you want looks to be impossible, it makes sense to give up fighting for that thing you want.

In other Dodgers news, there?s a new billionaire mogul type who is reported to be interested in buying the team. His name is Tom Barrack, he?s in real estate and he used to play rugby at USC. ?You can read all about him here. Frankly, you?ve seen one former rugby-playing real estate mogul, you?ve seen them all.

Source: http://hardballtalk.nbcsports.com/2012/01/11/dodgers-fox-settle-tv-rights-dispute/related/

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Rocstor outs Amphibious hard drive, keeps top-secret docs safe from wandering peepers

If you're a fan of keeping all of those precious work files locked down tight on your portable storage device, Rocstor has a rugged new option for you. The company has announced the launch of Amphibious at CES 2012, a portable hard drive that sports real time encryption and offers not one, but two-factor authentication via Smart Card and keypad -- keeping those top-secret merger plans shrouded in mystery. Incorporating a SATA HDD (up to 1TB) or SSD, the device connects via USB 2.0 or Firewire 800 and protects data behind AES-256 bit key strength and a FIPS 140-2 validated crypto module. In terms of durability, the pocket-sized Amphibious is housed in an aircraft grade aluminum alloy case. You can take a look at the full list of specs in the PR after the break and get ready to snag one for yourself during Q1 of 2012.

Continue reading Rocstor outs Amphibious hard drive, keeps top-secret docs safe from wandering peepers

Rocstor outs Amphibious hard drive, keeps top-secret docs safe from wandering peepers originally appeared on Engadget on Tue, 10 Jan 2012 08:00:00 EDT. Please see our terms for use of feeds.

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